ISSN 1662-4009 (online)

ey0016.11-5 | Tracking, Programming, and Epigenetics | ESPEYB16

11.5. Acceleration of BMI in early childhood and risk of sustained obesity

M Geserick , M Vogel , R Gausche , T Lipek , U Spielau , E Keller , R Pfaffle , W Kiess , A Korner

To read the full abstract: N Engl J Med. 2018;379(14):1303–1312.This analysis of longitudinal BMI data from early childhood to adolescents in 51,505 German subjects (CrescNet patient registry) allows a new insight into BMI development, specific dynamics and BMI trajectories from childhood to early adulthood.The exact pattern and time course of weight gain duri...

ey0020.2-6 | Important for Clinical Practice | ESPEYB20

2.6. Growth patterns of children with short stature in adulthood according to auxological status and maturity at birth

R Pfaffle , M Knupfer , M Gobert , M Vogel , R Gausche , C Beger , E Keller , A Korner , U Thome , W Kiess

Brief summary: This retrospective longitudinal study included 5698 patients with multiple height measurements since birth to the near-adult age. The aim was to define different growth patterns of children from birth to 18 years corrected for gestational age, sex and auxological status at birth in order to early identify children at risk for adult short stature. Adult height was significantly reduced in preterm and/or in small-for-gestational-age (SGA) children, with no sex dif...

ey0018.4-6 | Growth Hormone Therapy: Safety | ESPEYB18

4.6. Long-term mortality after childhood growth hormone treatment: the SAGhE cohort study

L Savendahl , R Cooke , A Tidblad , D Beckers , G Butler , S Cianfarani , P Clayton , J Coste , ACS Hokken-Koelega , W Kiess , CE Kuehni , K Albertsson-Wikland , A Deodati , E Ecosse , R Gausche , C Giacomozzi , D Konrad , F Landier , R Pfaeffle , G Sommer , M Thomas , S Tollerfield , GRJ Zandwijken , JC Carel , AJ Swerdlow

Lancet Diabetes Endocrinol. 2020;8(8):683–692. doi: 10.1016/S2213-8587(20)30163-7. PMID: 32707116SAGhE is a large independent European consortium including eight different countries (Belgium, France, Germany, Italy, The Netherlands, Sweden, Switzerland, and the UK) which was set up to evaluate the long-term safety of rhGH in a large cohort (>24 000) of young adult patients t...